WHAT IS SUPINE HYPERTENSION?

Supine hypertension is high blood pressure when lying down. You may have high blood pressure when lying down for many of the same reasons you have low blood pressure when standing up. The damage caused by your nervous system disorder may also affect your body's ability to control blood pressure when lying down.

Work with your healthcare provider as NORTHERA may cause or worsen supine hypertension (high blood pressure while lying down) in patients with nOH. If supine hypertension is not well-managed, NORTHERA may increase the risk of cardiovascular events, particularly stroke. You can reduce the risk of supine hypertension by keeping your upper body raised when lying down. You can do this by raising the head of your bed.

IMPORTANT SAFETY INFORMATION

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WARNING: SUPINE HYPERTENSION (this is high blood pressure while lying down)

When lying down, elevating the head and upper body lowers the risk of high blood pressure. Check your blood pressure in this position prior to starting and during NORTHERA treatment. If you experience high blood pressure, talk to your doctor about your NORTHERA treatment.

IMPORTANT SAFETY INFORMATION

EXPAND

WARNING: SUPINE HYPERTENSION (this is high blood pressure while lying down)

When lying down, elevating the head and upper body lowers the risk of high blood pressure. Check your blood pressure in this position prior to starting and during NORTHERA treatment. If you experience high blood pressure, talk to your doctor about your NORTHERA treatment.

For more information, please see the full Prescribing Information, including Boxed Warning for supine hypertension.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.