NORTHERA® (droxidopa) Dosing 

When taking NORTHERA, always follow your healthcare provider's instructions.

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Capsules shown are not actual size.


Your healthcare provider will likely gradually increase, or titrate, your dose of NORTHERA. This is how titration works:

  • Do not take NORTHERA if you have a known allergy to NORTHERA or its ingredients
  • When you first start treatment, your healthcare provider will start with a low dose of NORTHERA taken up to 3 times a day
  • Based on how you respond to treatment, your healthcare provider will likely increase your dose, a little at a time, until you and your healthcare provider have found the dose that best manages your symptoms
  • Try to take your medicine as scheduled. If you miss a dose:
    • Take your next dose at the regularly scheduled time
    • Do not take 2 doses to make up for the dose you missed
  • Take your NORTHERA capsules whole
  • NORTHERA may be taken with or without food, but it should be taken the same way every time
  • NORTHERA may cause allergic reactions. Stop taking NORTHERA and contact your doctor right away, or go to the nearest emergency room if you experience any signs or symptoms of an allergic reaction such as: fast heartbeat, nausea, vomiting, swelling, trouble breathing, hives, or rash. NORTHERA contains tartrazine (FD&C Yellow No. 5), which may also cause an allergic reaction, especially if you have had a reaction to aspirin
  • Do not stop taking NORTHERA without first talking with your healthcare provider
  • You should not breastfeed during treatment with NORTHERA

When NORTHERA was studied in clinical trials, doses were increased every 1 to 2 days.

Blood Pressure Readings

Talk with your healthcare provider about how to measure your blood pressure and what readings are right for you. Recording your blood pressure can help you and your healthcare provider check for high blood pressure when lying down (supine hypertension), which may happen in patients with symptomatic neurogenic orthostatic hypotension (nOH).

IMPORTANT SAFETY INFORMATION

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WARNING: SUPINE HYPERTENSION (this is high blood pressure while lying down)

When lying down, elevating the head and upper body lowers the risk of high blood pressure. Check your blood pressure in this position prior to starting and during NORTHERA treatment. If you experience high blood pressure, talk to your doctor about your NORTHERA treatment.

IMPORTANT SAFETY INFORMATION

EXPAND

WARNING: SUPINE HYPERTENSION (this is high blood pressure while lying down)

When lying down, elevating the head and upper body lowers the risk of high blood pressure. Check your blood pressure in this position prior to starting and during NORTHERA treatment. If you experience high blood pressure, talk to your doctor about your NORTHERA treatment.

For more information, please see the full Prescribing Information, including Boxed Warning for supine hypertension.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.