What Is Symptomatic Neurogenic Orthostatic Hypotension?

Orthostatic hypotension (OH) is a sustained drop in blood pressure that occurs after standing, and it may happen for a variety of different reasons.

When OH is associated with nervous system disorders, such as Parkinson’s disease (PD), multiple system atrophy (MSA), or pure autonomic failure (PAF), it's called neurogenic orthostatic hypotension (nOH). People living with nOH may experience symptoms when they stand, such as lightheadedness, dizziness, or the feeling that they are about to black out. Others can be asymptomatic, meaning they may not experience symptoms.

Do not take NORTHERA if you have a known allergy to NORTHERA or its ingredients.

MY EXPERIENCE WITH SYMPTOMATIC nOH

Watch this video to get a better sense of what symptomatic nOH is and how it could affect those who live with this manageable condition.

What's Causing My Drop in Blood Pressure?

Healthcare providers believe that damage caused by nervous system disorders, such as PD, MSA, and PAF, affects blood pressure in that:

  • Your nervous system may not be able to make or release enough norepinephrine
  • Without this chemical, the blood vessels may not receive the message that they need to constrict, and not enough blood may reach your brain
  • The reduced blood flow to your brain may lead to symptoms of nOH, such as dizziness, lightheadedness, and the feeling that you're about to black out
IMPORTANT SAFETY INFORMATION

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WARNING: SUPINE HYPERTENSION (this is high blood pressure while lying down)

When lying down, elevating the head and upper body lowers the risk of high blood pressure. Check your blood pressure in this position prior to starting and during NORTHERA treatment. If you experience high blood pressure, talk to your doctor about your NORTHERA treatment.

IMPORTANT SAFETY INFORMATION

EXPAND

WARNING: SUPINE HYPERTENSION (this is high blood pressure while lying down)

When lying down, elevating the head and upper body lowers the risk of high blood pressure. Check your blood pressure in this position prior to starting and during NORTHERA treatment. If you experience high blood pressure, talk to your doctor about your NORTHERA treatment.

For more information, please see the full Prescribing Information, including Boxed Warning for supine hypertension.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.